The phrase "are problematical for" is correct and usable in written English.
It can be used to indicate that something presents difficulties or challenges for a particular subject or group.
Example: "The new regulations are problematical for small businesses trying to comply with the changes."
Alternatives: "pose challenges for" or "create issues for".
He said Medco's five-year contract with Merck, disclosed in its government filings, was problematical for its future business.
This magnitude dependence is problematical for the EEPAS model, which implicitly assumes that p I is independent of magnitude.
Input RSS vectors of such high dimensionality are known to be problematical for simple classification and regression methods.
This target class has been previously shown to be problematical for in silico target prediction due to the promiscuity of the targets [39].
Stable walking is problematical for many Parkinson's disease (PD) patients, sometimes experienced as "Freezing of Gait" (FOG), a brief interruption of their natural walking rhythm usually limited to advanced stages of PD.
This condition is problematical for public health and biodiversity specialists because, despite appearances in the field, the specialist parasite is not nearly as host specific as they appear Brooks and McLennan (2002) called them "faux specialists").
We surmised that the DNA shearing and size selection processes used in most genome sequencing projects might be problematical for the sequencing and assembly of telomeres.
However, this equation cannot represent the case where C is zero and is problematical for this reason when baseline or placebo data are modeled.
I realize that QPCR is problematical for genes that are expressed in multiple tissues if the effect one is interested in is restricted to just one tissue, but some of the genes studied seem to be expressed primarily in the coelomic pouches (at least at some stages) and could therefore be analyzed by QPCR or other quantitative methods.
Your criteria for evaluating the question in your article's headline are problematical.
