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The diseases are called complex, meaning that several mutated genes are probably implicated in each.
Although statistical significance was not reached, the four upregulated genes were also higher in patients with other examined complications, including CAD, retinopathy, and nephropathy, suggesting that these genes are probably implicated in all diabetes complications.
However, this signature has been mainly evaluated only in one compartment, the cytosol, without simultaneously considering the putative variation in other compartments which are probably implicated in the generation of specific cellular signatures.
The results, as shown in Additional file 4 Table S7, reveal that a large number of genes with various predicted or known functions, including some known virulence-related genes, are potential targets of sRNA- Xcc1, sRNA- Xcc3 and sRNA- Xcc4, suggesting that these sRNAs are probably implicated in the regulation of different cellular processes including pathogenesis.
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As Naa10, due to its numerous substrates, is probably implicated in a multitude of cellular processes, a generalized, multi-system knockdown phenotype is to be expected.
Therefore, Fr2 is probably implicated in producing the appropriate behavioral response to situations that require immediate attention (Hoover and Vertes 2007).
In both genes, a patient-specific mechanism, which can distinguish the two different patterns, is probably implicated.
Hypothesizing that genes that are connected to one or more known disease genes ("seed genes") are also probably implicated in the same disease, our goal is to find such novel candidate genes with "strong" associations to the seed genes.
In addition, genes related to septal sealing and cytoskeleton organisation (hex and vpr) are also probably implicated in the stabilisation and maintenance of mycelium and yeast cells in the environment and at 37°C in the human host.
These findings indicated that apoptosis was also probably implicated in the developmental neurotoxicity of silver NPs.
Owing to the fact that the three eukaryotic replicases (Polα, Polδ and Polε) also belong to the B-family, this PolB is most probably implicated in genomic duplication in Hfx.
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