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Thus, Bmi1 and Mel18 have opposing functions and are present in distinct complexes.
The fact that the distribution maps of these two elements is complementary is an indication that these elements are present in distinct layers, one on top of another.
Species that are present in distinct sub-populations must be considered in terms of metapopulations - a group of several local populations linked by immigration and emigration.
In additional experiments, in which we conducted affinity purification of MEL18 in cells expressing FLAG-tagged RING1 and HA-tagged RING2, or vice versa, we demonstrated unequivocally that RING1 and RING2 are present in distinct complexes (Supplementary Fig. S2).
Many of these genes are present in distinct isoforms in fibrillar versus tubular muscles.
In cardiomyocytes, specific NOS isoforms are present in distinct intracellular localizations allowing NO to have a coordinated and restricted interaction with colocalized effectors [ 21, 82].
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Most proponents of this approach combine the claim that sensory processing operates in a discrete manner with the further claim that stimuli presented within any given perceptual windows appear simultaneous (or are not distinguishable from one another at all); only stimuli which are presented in distinct perceptual moments give rise to experiences which seem successive.
These studies indicated that Sox2 is present in distinct protein complexes that vary considerably in size.
It is noteworthy that monocyte-derived macrophages and DCs were present in distinct branches, along with several macrophage cell lines (J774, DH82, THP-1) and a T cell line (C8166 cells).
The two proteins were present in distinct cells within epithelium.
The same symbiovar may be present in distinct species as a consequence of the lateral transfer of symbiotic plasmids or islands.
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