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Sea surface temperatures are predicted to further rise by 2 3°C over the 21st century [5].
The prevalence and mortality of COPD are predicted to further increase in the next decades [ 2].
We found three distinct expression patterns of miRNA genes clusters that are predicted to further regulate numerous pathways and biological processes involved in wound repair.
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Hypokalemia would be predicted to further reduce the current density of IKr channels already impaired at baseline by the P1086fs+32X mutation in our patient, thereby markedly prolonging the QT interval and increasing the risk of torsade arrest in our proband.
As a result, ocean pH has already dropped by 0.1 from the pre-industrial era, and it is predicted to further decline by an approximately an additional 0.3 units by the year 2100 [5] [6].
Since Ihh plays an important role in maintaining chondrocyte proliferation, the reduced number of Ihh producing prehypertrophic chondrocytes in c-Myc mutants and the apparent reduction in Ihh expression in those cells (Fig. 6C, C' and Fig. 8B, C) is predicted to further diminish both chondrocyte and osteoblast proliferation.
The wild-type (wt) HGSNAT intron 3 donor splice site is relatively weak, and the c.370A>T variant is predicted to further weaken it (Table 1).
Lastly, continued optimization of the expression cassette design might be predicted to further improve the yield of FIX protein per transduced cell.
The prevalence and incidence of renal replacement therapy (RRT) has increased dramatically and is predicted to further increase 29%and47%47 % respectively until 2020 [ 2].
Loss of p16 function through methylation-mediated gene silencing, mutation, or gene deletion, as is commonly found in melanoma [ 1], would be predicted to further increase ROS levels and correspondingly increase oxidative damage.
The life expectancy in the UK increased by 5.3 years for men and 4.7 for women over the last two decades and is predicted to further increase in the next twenty years (Oeppen & Vaupel, 2002; Office for National Statistics 2014).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com