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Nearly all of these indel mutations are predicted to create frameshift mutations although a few frame-preserved mutations are also observed.
These mutations create an alternate upstream start codon and are predicted to create truncated IRF6 proteins.
Age increases in reproductive output are predicted to create a strong selection for increased longevity [ 7].
Of the seven significantly associated SNPs, risk alleles for four (rs5934770, rs2270112, rs12861247, rs17335568) are predicted to create new transcription factor binding sites (http://www.cbrc.jp/research/db/TFSEARCH.html).
Variants that are predicted to create a cryptic site upstream or overlapping a natural site of the opposite polarity (i.e. cryptic donor upstream of a natural acceptor) have been reported, which would be inconsistent with established splicing mechanisms.
Large hydrophobic residues L8 Phe (F) and L10 Ile (I) are predicted to create a favorable protein interaction interface, whereas basic residue L14 Lys (K) neutralizes ECs with the DNA backbone (Ma et al. 2007).
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To address the validity of our SNP predictions and their utility for genotyping we identified 27 that were predicted to create a polymorphic restriction enzyme site and used this to genotype individuals from the inbred and randomly mated Brookings population using CAPs (see Methods).
The airport alone is predicted to create employment for 1,500 people by 2016.
Gene duplication has been predicted to create gene diversity because the duplicated genes can diverge to acquire new functions (Ohno 1970; Roth et al. 2006).
Virtual reality (VR) is predicted to create a paradigm shift in education and training, but there is little empirical evidence of its educational value.
The mutated allele consisted of a 13 base-pair deletion that was predicted to create a frameshift mutation after amino acid 25.
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