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Since all the substitutions introduced in the HA sequence are postulated to destabilize binding, our assays measure a negative cooperative effect on complex stability.
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At low pH, protonation of the beta N terminus and His 147 HC3 beta within these clusters is postulated to destabilize the R-state and promote the acid-triggered, allosteric R-->T switch with concomitant O2 release.
The P3 mutation, Lys to Asp, is postulated to destabilize the H-bonds between α9 Gln and α62 Asn with the carbonyl of P4.
These are the satellites that are postulated to be captured.
Epigenetic mechanisms are postulated to mediate migraine susceptibility.
Nitration of these tyrosine residues has been postulated to cause conformational changes that destabilize the active site, thereby contributing to the ability of ONOO− to decrease ACO2 activity [ 24].
Organizational factors have been postulated to be a major reason.
The relationship is postulated to follow the Mooney Rivlin function.
The growth is postulated to occur in two stages.
Ncd was postulated to perform both functions.
Then, two possible explanations were postulated to explain the results.
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