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Decreased expression of ERα and increased expression of ERβ are persistent changes observed in mammary epithelium of parous rodents [ 8].
Altogether, these findings tend to support the notion that there are persistent changes in growth regulatory pathways in the parous mammary gland.
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As shown in Figure 4, there were persistent changes in baseline HR and HRV, with the differences being most pronounced after the series of 14 days with unusually high Ni values.
Thus, any contribution of maternal diet to offspring body composition at this stage is more likely to represent persistent changes rather than reflect nutrient or mRNA deposition in the embryo.
Even if the treatments resulted in real changes in subjects' beliefs immediately after the experiment, we do not know that these changes are persistent.
The findings on repeat biopsy are quite striking because in patient # 1, there has been resolution of glomerular and arteriolar evidence of TMA, whereas these changes are persistent in Case # 2. Persistent TMA in Case # 2 was associated with endothelial damage, fibrinoid necrosis and an obliterative vasculopathy which may explain persistence of kidney failure with dialysis-dependence.
However, when CVSC is ≤1e-11, persistent changes are unlikely to occur.
Similar to Ultima Underworld, another Looking Glass Studios project, the environment in System Shock 2 is persistent and constantly changes without the player's presence.
This pain will be persistent and not change with your monthly menstrual cycle.
There were many persistent changes at JHU (Fig. 6), and most were coseismic drops.
Finally, elastin deposits were measured as a total elastin amount to provide information regarding changes in alveolar walls, septa and blood vessels, and whether these changes were persistent.
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