Sentence examples for are particularly refractory from inspiring English sources

These data indicate that PV cells are particularly refractory to MD, suggesting that different cortical subpopulation may show different response to MD.

Importantly, hypoxic cells are particularly refractory to treatment and tend to have an increased metastatic potential [ 1, 3].

Membrane complexes such as the SJ are particularly refractory to biochemical and structural analysis owing to their hydrophobicity and large size.

It is interesting to note that these effects are the result of RNAi-mediated knockdown of prohibitin genes mainly in non-neuronal C. elegans cells, given that neurons are particularly refractory to RNAi[ 32].

This has been an area that's been particularly refractory to drug discovery and development, because we don't understand, really, the biology of the diseases very well.

Our study indicates that PV cells can be particularly refractory to MD effects.

Second, some proteins might be particularly refractory to protease digestion.

Interestingly, Spencer et al. demonstrated that guanine adducts detected by P-postlabeling were the major adducts following the incubation of cell lines with racemic - anti-DB[ a, l]PDE, and these adducts were particularly refractory to the removal by nucleotide excision repair (NER) system in several human NER proficient (NER+) cell lines.

These are particularly encouraging results because the trial recruited mainly platinum-resistant or refractory patients, in whom a RR to chemotherapy of 15% would be expected [40].

Silica refractories have good load resistance at high temperatures, are abrasion-resistant, and are particularly suited to containing acidic slags.

They are particularly nutritious.