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The phrase "are particularly problematic in" is correct and usable in written English.
It can be used to highlight specific issues or challenges associated with a particular context or subject matter.
Example: "These regulations are particularly problematic in rural areas where access to resources is limited."
Alternatives: "are especially challenging in" or "pose significant issues in".
Exact(27)
Such incentives are particularly problematic in a case involving leaks.
Crossings are particularly problematic in winter months, and there have been cases of sinking and drowning.
In a statement, the organization noted that these chemicals are particularly problematic in sportswear, because "sweat and movement friction can facilitate the migration of hazardous substances from the fabric to our skin".
These symptoms are particularly problematic in professional voice users.
Invasive neophytes - such as members of the Elodea genus - are particularly problematic in this regard.
For this reason, we did not include MFCC, since they are particularly problematic in terms of redundancy and interpretation [6].
Similar(31)
The delay is particularly problematic in Florida because of its demographics.
"This is particularly problematic in children because the effects of concussion last longer and their brains are far more vulnerable.
This has been particularly problematic in Egypt and Libya.Another problem is linking a specific asset with corruption.
But analysts say that the defense of Egypt's pipeline network would be particularly problematic in the event of terrorism.
The quest for justice is particularly problematic in Bangladesh, where politics is a deeply personalized, polarizing business, and almost all of the accused are political enemies of the current government, led by Sheik Hasina Wazed of the Awami League Party.
More suggestions(12)
are particularly troubling in
are exceptionally problematic in
are particularly troublesome in
are particularly complex in
are particularly dangerous in
are particularly sensitive in
are extremely problematic in
are particularly difficult in
are particularly severe in
are particularly challenging in
are particularly complicated in
are particularly valuable in
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com