Sentence examples for are particularly challenging from inspiring English sources

Experts say the middle-school years are particularly challenging.

All acetabular fractures are difficult to treat surgically, but there are four types involving two columns that are particularly challenging.

The course's three signature holes are particularly challenging.

Green trade barriers are particularly challenging for small businesses, which have fewer resources to monitor and address changes in overseas markets.

Labile interactions, such as the interaction between p120-catenin and the E-cadherin complex, are particularly challenging.

These patients are particularly challenging.

Dose adjustments in insulin-requiring diabetic patients are particularly challenging.

The associated problems of parameter estimation (model calibration) and optimal experimental design are particularly challenging.

More appropriate targeting of rehabilitation therapy could be achieved through more informed care planning, but rehabilitation decisions are particularly challenging.

The cancer-relevant transcription factors STAT5a and STAT5b are particularly challenging small-molecule targets because their SH2 domains are 93%% identical on the amino acid level.

Existing techniques are particularly challenging for use in developing country settings, where vitamin A deficiency remains a major public health problem.