The uncertainties caused in Kalman-type filters, due to the inaccurate selection of model parameters are overcome using an EM algorithm.
The low coverage provided by fHbp could be overcome using a multicomponent vaccine.
We call this modeling difficulty the trifold identification problem and show that it may be overcome using a test based on the quasi-likelihood ratio (QLR) statistic.
That problem has now been overcome, using a network of recoverable seismometers deployed on the seabed by scientists from the Scripps Institution of Oceanography and the Woods Hole Oceanographic Institution.
The major problem, handling arbitrary variations in the model geometry, is overcome using a modified form of the Woodcock neutral-particle tracking algorithm.
Sliding mode control has limitations due to the phenomenon of chattering which damages the actuator; this problem is overcome using a continuous function.
New chemistry for preparing polypropylene (PP) thermosets is described, wherein radical degradation suffered during conventional peroxide treatment is overcome using a nitroxyl additive that bears a polymerizable functional group.
However, major problems like cell survival, control of differentiation and engraftment remain and may be overcome using a tissue engineering strategy, which provides a 3D support to grafted cells improving their survival.
The difficulty of terrain data acquisition within giant kelp forests was overcome using a narrow single beam sonar system and the development of processing algorithms that resulted in high resolution (10 m) models of bathymetry and algal patch structure.
