Sentence examples for are on pathway from inspiring English sources

Indeed, whilst oligomers are commonly observed during fibril formation, there is as yet no definitive proof that such species are on pathway to the fibrillar form.

These intermediates are on pathway and eventually all remaining r-proteins, including S5 and S12, are incorporated into the mature 30S subunit.

The Δ rimP intermediates are on-pathway and are eventually incorporated into 70S ribosomes, based on pulse-labeling analysis.

In order to confirm that the incomplete 30S particles are on-pathway assembly intermediates, the ΔrimP strain was pulse-labeled and the f L values of r-proteins in 70S ribosomes were measured for various time periods post-pulse.

The data show that primary binding r-proteins such as S4 that are highly abundant in assembly intermediates in the ΔrimP strain have large values of P (p = 0.12 or 12%), confirming that the assembly intermediates are on-pathway.

Together, these pulse-labeling data show that the intermediate assembly species are on-pathway and that incorporation of S12 and late-binding proteins S2, S21 and S3 is delayed during 30S assembly in the absence of RimP.

Our results are consistent with a hierarchical model of folding, where the intermediate consists of native-like interactions, is on-pathway, and is productive for folding.

What alternative mechanism is possible given that looping and extensive translocation are unlikely to be on-pathway to DNA cleavage?

The latter mechanism necessarily invokes the transient formation of a high-energy intermediate that is on-pathway for folding, as shown in Figure 1c.

Rather, we provide positive evidence that fucosylated glycoproteins mediate CTB binding and internalization and, further, that fucose-dependent internalization of CT is on-pathway to host cell intoxication.

The biomarkers studied are on pathways of inflammation, along with cytokines such as interleukin-6 and tumor necrosis factor-α, previously shown to be closely related to adiposity.