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The phrase "are often small by" is not correct and does not convey a clear meaning in written English.
It may be intended to describe something that is frequently small in comparison to something else, but the phrasing is awkward and incomplete.
Example: "The results of the experiments are often small by comparison to previous studies."
Alternatives: "are frequently small in relation to" or "are commonly small compared to".
Exact(1)
Although DCIS masses are often small by comparison to IBC masses, DCIS is typically detected through mammography or self-examination.
Similar(59)
Although K0 is a matching point at saturation in the description of unsaturated hydraulic conductivity, it is not necessarily equal to KS but it is often smaller by about one order of magnitude (Schaap & Leij, 2000).
But counterfeit operations are often small fly-by-night firms that operate out of shacks.
Community energy schemes are often small enterprises run by volunteers, designed to generate income for their area.
These are often small firms, hampered by their lack of financial resources and often unable to develop the final products by themselves.
All species of the P. alpicola group are rather rare, and their populations are often small and endangered by human activities.
These programs are often small scale projects run by charismatic leaders.
What is more, the arthritic moose were often small, measured by the length of the metatarsal bone in the foot.
Regarding 2) the sample size used for calculation of reference limits is often small, exemplified by 33 dogs in one of the laboratories used in this study.
(It was often small children, annoyed by their silly angel wings, who did so).
Also, the magnitude of changes seen by microarrays is often smaller than the corresponding changes seen by RT-PCR.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com