The phrase "are often problematic and" is correct and usable in written English.
It can be used when discussing issues or challenges that frequently arise in a particular context or situation.
Example: "Many policies in the organization are often problematic and lead to confusion among employees."
Alternatives: "frequently cause issues and" or "often present challenges and".
The drugs listed in recent recommendations from the American Geriatrics Society are often problematic and warrant special attention.
Small-strain stiffness and damping ratio are the key parameters for modeling the dynamic behavior of soils, but they are often problematic and onerous to obtain under field conditions.
Immuno-electron microscopy (immuno-EM) affords higher resolution and has provided valuable information about the disposition of individual proteins within centrioles, basal bodies and centrosomes, but antigen preservation and accessibility are often problematic and co-localization studies challenging.
The translation of preclinical results to the clinical setting is often problematic, and it can be assumed that this is the case in PET research as well.
Under-recruitment to randomised controlled trials (RCTs) is often problematic and there may be particular difficulties in recruiting patients with severe mental illness.
Patient flow from intensive care to acute care units is often problematic and many discharges from intensive care to acute care are unsuccessful on the first attempt.
Canine generalized demodicosis associated with hyperadrenocorticism is often problematic and might be intractable.
This is in contrast to observational studies in which selection bias is often problematic, and in which it is very difficult to adjust for unknown confounders [ 5].
Diagnosis is often problematic and the need for source control adds a level of complexity to the management of the patient.
However, sampling target tissues from humans is often problematic, and data derived from tissues not routinely available to clinicians limits the diagnostic utility of this approach.
Immunosuppression is a common complication associated with long-term hyperadrenocorticism, which renders dogs prone to the development of secondary demodicosis and is often problematic and might be intractable [ 3].
