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Commercial instruments are often optimized for small molecules and peptides but not for oligosaccharides.
Conditions in the laboratory are often optimized for growth and reproduction, reducing the natural ability of flies to escape predators or compete for food and mates.
Cell culture conditions are often optimized for the variety of viruses and experiments performed in a laboratory as well as for the availability of reagents and thus cannot be prescriptive.
As a conclusion, let us mention that the bias outlined in the present article does not only affect biomedical articles, but also potentially methodological articles, where tuning parameters or method features are often optimized based on the data sets that are subsequently used for evaluation and comparison [ 39].
Hybrid cars are often optimized for fuel efficiency over comfort and even cost-efficiency, but can save a lot of gas by regenerative braking and provide plenty of comfort at low speed in stop-and-go commuting.
In additive manufacturing (AM) processes, part and process attributes are often optimized with build orientation/tool-path direction.
Similar(48)
However, selection is often optimized to improve animals within pure lines or breeds [ 1].
First-generation short-read aligners were often optimized for ungapped alignment whereas today's programs can deal with longer read lengths and gaps.
Microscopes are often not ergonomically optimized and do not allow a neutral sitting position, requiring the pathologist to bend forward [ 3, 8, 34].
These approaches try to capture the complexity of the ADMET processes via the unjustified use of a plethora of descriptors, rather than by focusing on the relevant chemico-biological interactions and building mechanistic models, which are often nonlinear in optimized coefficients.
Criteria to be optimized are often the energy consumption [2], the falling measure [3], the ZMP [4] and the jerk [5].
Related(20)
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are often fleeting
are often drunk
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are often pretty
are often ineffective
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Justyna Jupowicz-Kozak
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