18 Because adverse effects of AEDs are often concentration dependent, 9 the consistent plasma concentrations of USL255 may help minimize adverse effects.
The mode of cell death by toxic stimuli is often concentration dependent, with more likely apoptosis at low concentrations and necrosis at high concentrations.
However, since intracellular ion concentrations are often influenced by extracellular concentrations, one might expect that extracellular multivalent cations affect Min oscillations in vivo.
This is because proteins are often expressed at concentrations and forms that cannot be predicted from mRNA analysis [ 41].
Like many separation processes, ultrafiltration and reverse osmosis are often compromised by concentration polarization.
However, CSF concentrations are often considered the best available surrogate for brain target site concentrations in humans (3, 10– 10).
Moreover, experimental concentrations are often higher than those encountered in real-world situations, and the concentration levels used are constant rather than (highly) variable.
Foliar nutrient concentrations are often useful in inferring soil fertility and plant-soil interactions.
"The concentrations are often very low, but we are talking about pesticides that are extremely toxic: something like 4,000 to 10,000 times more toxic than DDT [dichlorodiphenyltrichloroethane]," he said.
However, the parameters for hydrogen treatment that are considered the optimum – very long anneals under low hydrogen concentrations – are often undesirable for practical reasons.
