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The genes included in a panel of amplicon sequencing (actionable genes) are genes that are often altered in different cancer types, and for whose alterations targeted therapies have been established or are in clinical development.
Contracts are often altered after the final bidder has been chosen, so the discipline of competition is removed.
The pharmacokinetics and pharmacodynamics of antidiabetic therapies for patients with type 2 diabetes are often altered in the context of chronic kidney disease (CKD).
Moreover, recently discovered DNA hydroxymethylation (5-hmC) is involved in transcriptional activation and its patterns are often altered in human diseases.
Other genes regulating apoptosis pathways are often altered in lung cancer such as RasSF1, the main tumor suppressor gene on 3p chromosome and the DAP kinase gene.
As always, the propagandists were attentive: foreign analysts who track the use of Photoshop on North Korean state images say that official pictures of Kim are often altered around his ears, possibly to mask some sort of blemish.
Similar(23)
Nevertheless, the hydraulic performance of these systems is often altered by physical and biological clogging.
One reason is that content is often altered to fit local tastes.
The script is adapted from Downey's own Off Off Broadway play of several seasons back, and is often altered.
After Wren, a handful of other architects created a few other City churches, and these too were often altered.
Electrochemical impedance spectroscopy is often altered by artefacts, arising from the improper electrode setup, stray capacitances and instrumental limitations.
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CEO of Professional Science Editing for Scientists @ prosciediting.com