Sentence examples for are of substantial concern from inspiring English sources

Suboptimal self-management (10), out-of-range glycemic control (11– 13), and more frequent complications and hospitalizations (14, 15) are of substantial concern during the transition years.

This is of substantial concern due to the increased mortality risk associated with underweight.

In particular, osteoporosis is of substantial concern in breast cancer survivors, especially in those diagnosed while still premenopausal.

From the dynamic discussions in the focus groups, we may conclude that this subject was of substantial concern to GPs.

Excitement about the possible advances resulting from molecular pathology has never been greater, and therefore the imposition of restrictions on this work that unnecessarily impede progress is of substantial concern.

A simultaneous balance of development of nanotechnology-based therapeutic approach and safety of human healthcare is a matter of substantial concern as the field of nanotechnology is promising yet.

These findings indicate that stigmatisation is an issue of substantial concern for people with T2DM, and has harmful consequences.

Background: The quality of medication use in older adults is a recurring problem of substantial concern.

However, there are a number of substantial concerns about exercise as a treatment option for patients.

Of substantial concern is the increasing problem of antibiotic resistance – a problem that ICUs both contribute to as well as suffer from [ 4].

The limitations of OK lenses are obvious, and the tight eyelids of Asian subjects are a substantial concern.