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The phrase "are of significant concern" is correct and usable in written English.
It can be used when discussing issues or topics that are important or troubling and require attention.
Example: "The recent increase in pollution levels are of significant concern to environmentalists and local communities."
Alternatives: "are a major issue" or "are a serious matter".
Exact(24)
Inpatient falls are of significant concern.
Bone disorders are of significant concern due to increase in the median age of our population.
With aging populations the increasing costs faced by healthcare providers are of significant concern.
Squealing brakes are of significant concern to the automobile industry, mainly because of the costs associated with warranty claims.
Heterogeneities in structure and stress within heart valve leaflets are of significant concern to their functional physiology, as they affect how the tissue constituents remodel in response to pathological and non-pathological (e.g. exercise, pregnancy) alterations in cardiac function.
Cancers linked to poor diet, lack of physical activity, alcohol consumption, smoking, and obesity are examples of preventable cancers that are of significant concern, particularly because of their impact on not only health but also workforce productivity and hence the national and global economy.
Similar(36)
Aging network assets, forced and unforced outages, and the way the networks are operated in a deregulated market are of significant concerns to integrate large wind farms in a distribution network.
Falls and associated negative outcomes in hospitalized patients are of significant concerns.
"There is some debris outside the church that is of significant concern".
Zoonotic diseases continue to be of significant concern for public health.
A blogger in Tehran said recent news was of significant concern to the country's online community.
More suggestions(14)
are of substantial concern
are of vital concern
are of considerable concern
are of significant relevance
are of particular concern
are of great concern
are of serious concern
are of immediate concern
are of global concern
are of special concern
are of huge concern
are of significant interest
are of major concern
are of notable concern
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com