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For those loci that did not exert pleiotropic effects, however, bivariate analyses generally produce results that are of lower significance than results generated by univariate analyses.
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if spots show inconsistent direction of regulation, then the gene p-value should be of lower significance than the most significant spot p-value.
The intraparticles diffusion is of lower significance in case of sandy soil than in clay soil.
Even though photosynthesis processes are also the most enriched processes of MMN, it is of lower significance (10−14) when compared to MLN (see image B in Table S12).
The analysis was only taken far enough to be confident of relationships between C. elegans and C. briggsae orthologues, and relationships implied by deeper branches will be of lower significance.
GO categories for the set of upregulated genes were of lower statistical significance, and included reproductive processes (p < 0.03) (Supplementary files 1, 2).
Categories that may be relevant to GSH activity, such as oxidoreductase activity, response to stress and cell redox homeostasis appeared to be less enriched and of lower significance (fold-enrichment of 1.8, 1.4, and 6.7 and P-values of 5.1 × 10-2, 8.9 × 10-2 and 6.4 × 10-3, respectively) and therefore potentially of reduced importance.
The signal transducers of lower significance tiers may be more important for tumor than norm and a therapeutic window opens.
A trend towards further upregulation of eRNA2 was seen in the presence of estrogen in TOX3-expressing cells, although this did not reach significance and was of lower magnitude than that seen for eRNA1.
"Lower" animals are of particular significance in terms of understanding the ancestral state, but have not been extensively studied.
They choose cases that are of legal significance or to unify lower court decisions.
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