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It is clear the AGA and AGG codons are being used and are not stop codons (as is the case in vertebrate mtDNAs), since they appear in the reading frames of protein encoding genes 117 times.
However this is not feasible for most disease causal variants (which are very rare by nature) and other lines of evidence such as animal knockouts, molecular studies and local sequence alignments (by using UniProt as mentioned above) are required to make a case for the causality of variants, especially mutations which are not stop gains (e.g., missense).
Similar(58)
We are not stopping there.
But Republicans are not stopping there.
And they are not stopping there.
And the parents are not stopping it".
When we go to commercial, those drivers aren't stopping, and we aren't stopping.
My ankles aren't stopping me".
But we aren't stopping there.
But spammers aren't stopping there.
But broadcasters aren't stopping there.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com