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The phrase "are not inconsequential" is correct and usable in written English.
It can be used to emphasize that something is significant or has importance, often in a context where one might underestimate its value.
Example: "The findings of this study are not inconsequential; they could change the way we approach treatment."
Alternatives: "are not trivial" or "are not insignificant."
Exact(20)
These are not inconsequential concerns.
Achieving things like that are not inconsequential".
The ethical issues involved in measuring stigmatized and illegal behavior are not inconsequential.
To the music industry, whose global revenue is some $32.2 billion, ring tone sales are not inconsequential.
Yet his attention to presentation, from the faux grids to the light boxes, suggests that formal matters are not inconsequential to him.
These are not inconsequential accomplishments for the offspring of an impoverished musician and a very bright woman who came to her responsibilities as a mother all too early in life.
Similar(40)
Feelings of solidarity aren't inconsequential or fruitless.
The individual tax brackets aren't inconsequential; they just weren't what Republicans were truly focused on.
It's not inconsequential.
This was not inconsequential, but terrorism is cheap.
Several thousand lives saved per year is not inconsequential.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com