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As we observe that ROS induced by AUL12 are not further increased by rotenone, we suspect that the two drugs act on the same biochemical process within Complex I. Notably, rotenone-dependent oxidative stress elicits autophagic death in cancer cells.
However, once these GCs are solubilized with detergents (e.g., Triton X-100) in the presence of Mn2+, they exhibit maximal cyclase activities, which are not further increased in the presence of ligands [ 31].
Similar(58)
Neurological improvement and lifespan were not further increased when the dose raised to 20 mg kg−1.
During hypoxia, 5 km for 5 h, SS mRNA in ADX rats was not further increased.
In strain DJ701, N-NO-IQ and N-NO-MeIQx elicited dose-dependent mutagenicity, which was not further increased in DJ702.
It added: "We wished to be sure that customer bills were not further increased unnecessarily, and that any increase was justified".
The ability of Calcisol to adsorb NH4+-N was high and was not further increased by biochar, which corresponds to no NH4+-N leaching from Calcisol regardless the biochar application rate.
We found that cisplatin induced a significant increase in Ki67-positive nuclei in TECs, which was not further increased in the HQH- and Dex-pretreated group (Fig. 2A), suggesting that HQH pretreatment-induced renoprotection does not occur through the increased renal regeneration capacity related to TEC proliferation.
OsRap2.6 transcripts were rapidly increased after chitin treatment and after 3 hr they were not further increased.
In contrast to this, the highest percentage was released from the SoSl1 sample, which is not further increased by spiking with Cd.
One animal in the sepsis group had a heart rate of 173 bpm after 24 h, and therefore, noradrenaline application was not further increased.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com