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Mammalian oocytes are not able to progress through the MI stage until all chromosomes have been properly attached to the bipolar spindle and are aligned at the metaphase plate[28].
Subjects with KL grade 4 are not able to progress and hence were excluded from this analysis.
These oligomers, however, are not able to progress to form amyloid fibrils because Zn II) does not induce the required structural changes near the N-terminus and His31.
However, PR-SET7-deficient cells are not able to progress beyond 1.5 cell divisions, as they are arrested in the G2 phase of the next cell cycle (Oda et al, 2009; Supplementary Fig S2C).
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However these cells were not able to progress towards leptotene stage compared to the Kit positive cells collected at 7dpp.
Overall, these results indicate that cycling cells with a blockade in SCD1 activity were not able to progress through the early stages of the cell cycle.
Finally, when the three step protocol was applied to mESCs, there was only a marginal increase in Brachyury and no concomitant increase in Sox17 (Figure 4C), suggesting that mESCs were not able to progress toward the definitive endoderm lineage under these culture conditions.
Six out of 25 (24%) were not able to progress to PCP.
Comparison of 3D-time-lapse observations of endodermal differentiation revealed that sgn3 is not able to progress from this 'string of pearls' stage, but only undergoes partial fusion of individual islands, leading to CASP1-GFP patches of heterogenous size.
Until the third workshop, however, there was no agreement, authorisation or resources for a network administration organisation and with the later cessation of Medicare Local funding, this potential role was not able to progress.
Apparently, even in those cases where spindles appear normal during the metaphase in apoptin-expressing cells, cells are not able to easily progress past the spindle assembly checkpoint (SAC) into anaphase.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com