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For the analysis of transcriptomics data, CEL files were normalized via quantile normalization using RMA [ 44] as implemented in the affy package [ 45] of R/Bioconductor suite of tools [ 46].
Data was normalized via a quintiles normalization and summarized using the Robust Multi-array Average (RMA) method [ 82].
Microarray data were normalized via the loess local intensity normalization method of Smyth and Speed [14], and probes were filtered for features having a normalized intensity of <30 aFU in both channels.
Microarray data were normalized via the loess local intensity normalization [ 7, 29], and probes were filtered for features having a normalized intensity of < 30 aFU in either channel.
For the first phase of the experiment with only the far detector running, the reactor electron antineutrino flux is normalized via reactor simulation.
PWS infants also fail to thrive during this time, even when nutrition is normalized via tube feeding.
For splicing analysis, core transcripts were normalized via RMA16 and filtered for detection above background level (p<0.00025).
Since this is normalized via pharmacological inhibition of the terminal enzyme of the ERC (the F1Fo-ATPsynthase) (see Fig. 2b), the oxidative phosphorylation of the HPC can be considered underperforming compared to that of the LPC.
Data were normalized via the minfi package (preprocessIllumina function).
Distributions of seriously skewed variables were normalized via logarithmic transformation.
Raw data were normalized via the MAS 5.0 algorithm, Gene Spring Software 11.0 (Agilent Technologies).
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