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Longitudinal studies are needed in order to reveal if the identified white matter microstructural changes are permanent.
Long-period, high-quality observations are needed in order to reveal whether there are any long-term trends in the incidence or strength of these layers, and to uncover their causes.
Larger studies with more sensitive methods are needed in order to reveal potential beneficial effects of pioglitazone on myocardial diastolic properties.
However, further in vivo and in vitro studies are needed in order to reveal many more unknown properties of this plant including both therapeutic and adverse effects.
Fourth, more longitudinal studies in the research field are needed in order to reveal the influence of (changes in) physical environmental attributes on different PA domains, in order to facilitate the development of appropriate and effective interventions for promoting PA.
In addition, our study demonstrates the presence of multiple independent adaption events of LAB species to different survival habitats, indicating that further analyses of more genes from representatives of additional LAB species are needed in order to reveal the molecular mechanisms underlying the adaptation of LAB species to various environmental survival niches.
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Further analysis is needed in order to reveal a possible effect on splicing or RNA stability.
Nevertheless, further work is needed in order to reveal the interactions between RNA silencing and photosynthesis.
In complex systems, also a "blunt-end" approach is needed in order to reveal the underlying system defect that allowed the opportunity for the error to occur.
In this exploratory study, 30 patients (20 patients in the BIP ETT group and 10 in the uncoated, standard ETT group) were judged to be needed in order to reveal statistically significant differences in the primary analyses.
Further studies are needed in order to clarify these mechanisms.
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