Sentence examples for are necessary for stem from inspiring English sources

Going forward, it will be important to systematically quantify the ROS levels generated by mitochondria and their targets that are necessary for stem cell proliferation, differentiation and exhaustion in a given stem cell model system.

To identify genes that specify the germline stem cell fate as well as genes that are necessary for stem cell proliferation and cell-cycle progression, genetic screens have been conducted in C. elegans for mutations that result in an abnormal Germ Line Proliferation (Glp) phenotype.

Second, the niche provides physical contact and anchoring that is necessary for stem cell self-renewal.

The results reported here may indicate that mesenchymal capability is necessary for stem cells derived from various sources to easily proliferate, loosen cell−cell connection, migrate and differentiate.

These results show that DDB1 is necessary for stem cells to renew their numbers and differentiate into blood cells in both developing and adult animals.

In contrast, other studies suggest that inhibition of FoxO protein activity or prevention of Wnt pathway disruption may be necessary for stem cell survival.

We also identified a homolog of nuclear transport factor Importin-α and found it to be necessary for stem cell function, differentiation, and patterning of regenerating tissues relative to the midline.

Therefore, the skin from the rat footpad or nude mice cannot grow hair because it does not contain competent DP cells, which are necessary for HF stem-cell induction of organogenesis and regeneration.

In embryonic stem cells, PcG proteins regulate stem cell pluripotency by maintaining repression of alternative lineage genes that are necessary for differentiation of stem or progenitor cells into various tissue types [35].

The pathway signatures include 54 hESC-related pathways that essentially belong to developmental signaling pathways such as the Wnt, Notch, Hedgehog, and Bmi-1 pathways that are necessary for the regulation of stem cell self-renewal and differentiation.

The experimental approach established in this study of genome editing the TERT promoter provides an experimental system to uncover cis-regulatory elements that are necessary for telomerase expression in stem cells and its transcriptional regulation upon differentiation.