Exact(1)
Here, we show that both, Stat3 and Stat5 are necessary for initial transformation.
Similar(59)
Finally, the derived sockets are employed as eye estimates in which DAISMI is employed to detect the stable approximate pupil-center position by averaging the positions of eyeball border vertices which is necessary for initial template orientation of DTBGE and the final movement displacement vector.
In developing bone, Hif-1 generated signals are required for angiogenesis, which appears to be necessary for initial specification of bone-forming osteoblasts.
This has been shown functionally in the progression of breast carcinomas, where Snail1 is necessary for initial invasion, and Zeb1/δEF1 and other E-cadherin repressor genes are involved in the maintenance of the mesenchymal phenotype, including motility [ 15].
The model proposed above where the fungus initially stimulates a stress response in the host and then uses this as a trigger for DON production is also consistent with the proposed role for DON later in the infection process rather than it being necessary for initial infection processes.
Similarly, the homeodomain transcription factor Nkx2.5 is necessary for initial development of the ventricular myocardium in murine models, although its role in maintenance of chamber identity was not previously defined (Biben et al., 2000; Lyons et al., 1995; Yamagishi et al., 2001).
The Secretary [of Transportation] may determine that eligible funds identified as inactive funds shall remain available for the purpose for which the funds were initially made available if the applicable State certifies that the funds are necessary for that initial purpose.
However, additional genetic alterations are necessary for overt transformation from an initial preleukemic clone [ 9, 10].
Autophagy-related (ATG) genes are necessary for the formation of the phagophore and autophagosomes, the initial steps in autophagy [ 82].
If ethics committee approval was necessary for the initial implementation of the registry, this must also be obtained for any amendments made after initial ethics committee approval, except where necessary to eliminate an immediate hazard to participants, or when the change involves only logistical or administrative aspects of the registry (eg, change of personnel, change of telephone number).
This outage is necessary for the initial rollout of the Libraries' new website.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com