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The physiological role of these anatomical structures is not fully understood, they are necessary for bone remodeling (the "canopy" theory) but the blood flow inside their lumen remains to be fully explored.
Osteoclasts are necessary for bone formation by the osteoblasts.
Adequate vitamin D concentrations are necessary for bone health and prevention of rickets.
Whether morphologic and phenotypic changes of malignant keratinocytes are necessary for bone invasion is the focus of future work [ 38].
As mentioned before, interconnected pores are necessary for bone tissue regeneration because they allow migration and proliferation of osteoblasts and mesenchymal cells besides vascularization.
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Cartilage is the first skeletal tissue to be formed during development, and is necessary for bone formation and movement.
Furthermore, bone formation, which appeared to occur by endochondral ossification, was achieved with the dual growth factor condition at protein concentrations that were more than an order of magnitude less than those reported previously to be necessary for bone formation.
In experiments with mice, the researchers found that a particular estrogen receptor is necessary for bone cells to replenish their numbers in response to mechanical strain.
We know that magnesium is necessary for bone health but it has a much broader scope than even I imagined.
The mechanism was thought to be a combination of reduced intake of vitamin K, which is necessary for bone health, and inhibition by warfarin of vitamin K-mediated carboxylation of certain bone proteins, rendering them nonfunctional.
Vitronectin receptor ligands have long been known to be necessary for bone resorption [58], but the finding that they are sufficient is novel.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com