For example, rule PM3 could be upgraded to strong if there were multiple observations of detection of the variant in trans (on opposite chromosomes) with other pathogenic variants (see section PM3 for further guidance).
There are multiple observations and related observations.
22 Himalayan Database data are non-independent, both longitudinally (that is, multiple observations per person) and by virtue of nesting within expeditions.
In educational programs, the inferences will usually be based on multiple observations of the execution of an EPA, but the inference is not conceptually different.
The underlying idea here is to average multiple observations of the same object segments.
This conclusion is supported by multiple observations of DNA methylation occurring after histone modification [4], [10], [11], [37] and examples of DNA methylation-independent silencing [12] [14].
This observation suggests that there are multiple combinations of cell motility, cell to cell adhesion and cell proliferation parameters which could replicate the experiment results and therefore a simple visual inspection of the population is insufficient to identify the mechanisms influencing the expansion of the cell colony.
However, a VSN with overlapping field of views (FOVs) is capable of providing multiple observations of the same object simultaneously.
Genome comparison of the sequenced strains reveals predominantly clonal structure of P. spp. lineages which is consistent with the multiple observations of asexual-only reproduction of P. spp. strains [ 1, 3- 6].
Although the inclusion of multiple targets (e.g., sexual partners, family, and close friends) in analyses of disclosure is common, the inclusion of multiple observations of the same type of target, such as sexual partners, is rare.
