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The phrase "are most appropriate when" is correct and usable in written English.
It can be used to indicate the specific conditions or situations in which something is deemed suitable or fitting.
Example: "These guidelines are most appropriate when addressing complex issues that require careful consideration."
Alternatives: "are best suited when" or "are ideal in situations where".
Exact(4)
Qualitative methods are most appropriate when a better understanding of a phenomenon is sought [ 74], or when a theory needs to be built.
BSOP are most appropriate when resecting 20%to50%0% of the breast volume [ 4], when the likelihood of major deformity escalates [ 2].
However, a study interested in comparing CMD internationally should consider utilising the Youden Index or the (0,1) method, as these methods are most appropriate when the study area encompasses regions with different case prevalences.
Alternative indices, such as the probability of classification [ 25], or the prediction strength such as the "margin-of-victory" measures adopted in Golub et al. [ 27], are most appropriate when there are multiple genuinely discrete outcomes, for which what is uncertain is the strength of evidence for class assignment.
Similar(56)
Early removal is most appropriate when presidents were fraudulently elected.
Term insurance is most appropriate when the need for protection runs for only a limited period; whole life insurance is most appropriate when the protection need is permanent.
Video CVs are a great opportunity to show your presentation skills and, according to Elizabeth Bacchus, career coach and founder of The Successful CV Company, they tend to be most appropriate when applying for creative or customer-facing roles in sales, media, marketing, PR and advertising.
The blackbody approximation used to derive these algorithms is most appropriate when the illuminant is daylight.
This approach is most appropriate when the source and target have the same class label space and one can transform Xs and Xt without context feature bias.
Ratios of flexural stress to compressive stress greater than two indicate the dominance of flexural stresses and suggest that flexural properties may be most appropriate when designing liners to resist buckling.
The enrichment design is most appropriate when compelling preliminary evidence suggests treatment benefit in only certain marker-defined subgroups, the all-comers design is useful when preliminary evidence regarding treatment effects in marker subgroups is unclear, and adaptive designs have the most potential in the setting of multiple treatment options and multiple marker-defined subgroups.
More suggestions(13)
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com