In fact, PT treatment was found to be more efficacious when compared to A treatment in many outcome measures.
Interestingly, the majority of preclinical data suggested that bisphosphonate treatment was more efficacious when administered after the establishment of osseous metastases.
Such interference has long been recognized; Sabin and his colleagues (Sabin et al. 1960) pointed out that the individual components of OPV were more efficacious when administered individually (as monovalent vaccines) than when administered together in a trivalent vaccine.
In previous trials, frovatriptan was able to decrease the overall duration of migraine attacks significantly [19], and it is more efficacious when taken during the mild, beginning phase of a migraine attack versus taken during the later severe phase [20].
Both drugs were more efficacious when treating UTIs, possibly due to the higher bacterial eradication rates.
Existing systematic reviews concluded that thoracoscopic talc insufflation/poudrage was more efficacious when compared to bedside chest tube talc slurry.
Additionally, antiemetics have been shown to be more efficacious when administered toward the end of surgery rather than at anesthesia induction [ 26, 27].
In some contexts, interventions may be more efficacious when framed as addressing community challenges, rather than as a treatment program for individuals [ 11, 45].
This appears to have been due to the fact that paclitaxel performed better weekly, whereas docetaxel was more efficacious when administered every 3 weeks.
However, bevacizumab was more efficacious when combined with PTX than DDP, a drug marginally active in our EOC models, so the final outcome of the combination also depends on the tumour sensitivity to chemotherapy.
