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In this review, we discuss recent literature demonstrating that distinct molecular pathways are modulated by specific environmental inputs, the output of which regulates leaf dissection.
This article surveys our understanding of transporters that are modulated by specific pathogens and the mechanism(s) involved, thereby illuminating targets that might be exploited for new therapeutic approaches.
Together, these data suggest that functions of EWS and TLS are modulated by specific structures of ncRNAs.
They are modulated by specific biochemical species [ 9, 10] or cell stress [ 11, 12] and both TRP channels may be involved in pathological conditions such as asthma, chronic obstructive pulmonary disease and chronic cough [ 13– 16].
The RGG domain in the carboxy terminus of EWS is important for the G-quadruplex specific binding, pointing that the functions of EWS and TLS are modulated by specific structures of ncRNAs [ 52].
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Recently, it was shown that several human multidrug resistance (MDR) ATP-binding cassette (ABC) proteins could be modulated by specific TKIs.
Allosteric enzymes exhibit a catalytic activity that is modulated by specific effectors, through binding to receptor sites that are distinct from the active site.
Structure function studies have revealed that fast macroscopic inactivation of CaV3.1 is modulated by specific residues in the proximal C-terminus and in the transmembrane domain IIIS6.
Discrimination of large numerosities thus emerges later in development and appears to be modulated by specific experience with social groups.
In addition, ethanol effects on the lipid dynamics could be modulated by specific ligands at MOP, as discussed in the following section.
In two different species, we also present evidence that the barrier separating conscious and unconscious states is amenable to genetic and pharmacologic manipulation and is modulated by specific arousal-promoting mechanisms.
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CEO of Professional Science Editing for Scientists @ prosciediting.com