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Islet non-β-cells from non-diabetic and diabetic human donors are modified via the transcription factors PDX1 and MAFA to produce and secrete insulin in response to glucose.
Generally, membranes are modified via five principal methods: (1) photo-initiated grafting and miscellaneous grafting; (2) plasma treatment; (3) physical coating/adsorption; (4) chemical reaction modification; (5) surface modification of membranes via nanoparticles impregnation [5].
Methionine-derived glucosinolates are modified via elongation of the side chain prior to entering the pathway for the synthesis of the core glucosinolate structure.
In metazoa, the ability of Ire1 to mediate mRNA decay of specific transcripts, termed Ire1-dependent decay (RIDD) [30] characterizes a third mechanism by which cellular protein levels are modified via ER stress.
The thread shared by these models is reinforcement-based learning of intrinsically motivated goal-directed actions based on exploratory movements, or motor babbling: Movements are generated erratically in response to a target and the mechanisms generating the movements are modified via positive reinforcement (Cangelosi and Schlesinger 2013).
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The Monte Carlo method is modified via the Doppler Broadening Correction Rejection DBRCC) method to implement the Doppler broadened scattering kernel.
Furthermore, the risk evaluation values can be modified via the credibility.
The precursors which were modified via acylamidation reactions behave as structural molecular bridges.
It is also possible that the wild-type SpdCas9 may be modified via protein engineering to enhance its chromatin modulating ability and nuclease activation efficacy.
The burning rate characteristics of solid composite propellants can be modified via different methods.
Then, in the presence of model parameter uncertainties, the proposed delayed feedback control law is modified via sliding mode scheme.
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