Sentence examples for are mediated upon from inspiring English sources

Several intracellular pathways are mediated upon activation of EGFR and/or HER2 by EGF.

Biologic activities of IFNs are mediated upon interaction with specific cell surface receptors and activation of intracellular signalling cascades (Ransohoff, 1998).

The biologic effects of IL-33 are mediated upon binding to T1/ST2 and the recruitment of IL-1RAcP, the common co-receptor of IL-1α, IL-1β, IL-1F6, IL-1F8, and IL-1F9.

Importantly, the effects appear to be mediated upon cognitive processes, rather than confounders such as affective behaviour or locomotion which are broadly unchanged by 11β-HSD1 deficiency (although aspects of locomotion at least are clearly impacted by ageing per se [312]).

The estimates for incident type 2 diabetes were mediated upon adjustment for BMI in the whole-population HR and 95% CI for frequent breakfast intake (HR 0.82 [95% CI 0.63 1.07]) and daily intake (0.81 [0.81–1.0.81.

Almost all metabolic processes are dependent upon or are mediated by electrolytes.

For these reasons we are confident in our assertion that the effects of MA upon HT29 cells are mediated in part by the expression of p53.

Its actions are mediated by specific G protein-coupled receptors that can be internalized upon ligand binding.

Importantly, not all actions of androgens upon the liver may be mediated by classical AR signaling.

In this module, activation of p38 by IKKβ can be direct, or it can be mediated through TAK1 acting upon the MKK3/MKK4.

It has been shown that this regulation is mediated by p53, which, upon differentiation, gets activated and represses Nanog expression by direct binding to its promoter.