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The phrase "are markedly different from" is correct and usable in written English.
It can be used to highlight significant differences between two or more subjects or items.
Example: "The results of the two experiments are markedly different from each other, indicating a need for further investigation."
Alternatives: "are significantly different from" or "differ greatly from".
Exact(60)
And finally, Solomon said, Mercury and the moon have strong hemispherical differences, meaning that each has two sides that are markedly different from each other.
New Yorkers are moving for reasons that are markedly different from those of 20 years ago.
Its theatrics are markedly different from those of previous execution videos.
The Ukrainian proposals are markedly different from currently existing lustration law in all three regards.
6. Tonight's game will be played under FIBA rules, which are markedly different from those applied in the NBA.
These experiences are markedly different from black men in occupations that are majority female, such as nursing.
The location, size, age, and presentation in the young are markedly different from that of adults.
His training methods are markedly different from the previous regime's: sessions are short and sharp with no stopping to rectify mistakes.
It presents results in ways that are markedly different from the list of 10 blue links that have long been an online standard.
Something interesting has emerged in voting patterns on both sides of the Atlantic: young people are voting in ways that are markedly different from their elders.
Furthermore, we showed that glargine elicited signaling events that are markedly different from those induced by insulin.
More suggestions(13)
are markedly divergent from
are considerably different from
are dramatically different from
are greatly different from
are markedly dissimilar from
are markedly distinct from
are appreciably different from
are substantially different from
are noticeably different from
are distinctly different from
are starkly different from
are radically different from
are markedly deviated from
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com