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The phrase "are many difficulties when" is not correct as it lacks a subject and verb to form a complete sentence.
You can use it in contexts where you want to discuss challenges or obstacles that arise in specific situations, but it needs to be part of a complete sentence.
Example: "There are many difficulties when trying to balance work and personal life."
Alternatives: "There are numerous challenges when" or "Many obstacles arise when".
Exact(1)
Although magnetotelluric sounding method applied to the land is advanced, there are many difficulties when it is applied to marine environment, one of which is how to lay magnetic field sensors down to the seafloor to complete measurements.
Similar(59)
There are many difficulties to overcome when trying to produce ready-to-use water matrix certified reference materials for hydrophobic organic compounds at low concentrations.
There are many difficulties that need to be addressed when considering effective mitochondrial transfection.
There are many difficulties for this high-dimensional multi-objective problem when traditional multi-objective optimization methods are used.
And there are many difficulties.
There are many difficulties, and the pressure is intense.
There are many difficulties with this approach, however.
Whilst in principle this is straightforward, there are many difficulties.
Here too there are many difficulties.
It was no longer as it used to be, and there were many difficulties to overcome when having sex.
There were many difficulties in building.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com