Sentence examples for are mainly internalized from inspiring English sources

In general, membrane proteins localized in lipid rafts are mainly internalized via caveolae and degraded by the proteasome, whereas membrane proteins in non-raft areas of the membrane tend to be internalized via clathrin-coated pits and degraded in lysosomes.

Analysis of the endocytotic pathway indicated that CPP-LNP were mainly internalized via macropinocytosis and heparan sulfate-mediated endocytosis.

Nanoparticle internalization assays performed with GBM-CSCs or Nestin negative cells cultured as two-dimensional (2D) monolayers or embedded in three-dimensional (3D) biodegradable-hydrogels of tunable mechanical properties, revealed that the AuNRs were mainly internalized by GBM-CSCs, and not by Nestin negative cells.

Non-opsonised Y. pseudotuberculosis is mainly internalized via the invasin-β1-integrin interaction in both these cell types [36], [45], [46], [47].

In contrast, the claudin-5 peptide is mainly internalized via the caveolae-mediated endocytosis as evidenced by the colocalization with respective tracers and vesicle markers, whereas the nonselective macropinocytosis seems to be involved in a less effective manner.

The EGFR is mainly internalized via CME upon exposure to physiological levels of EGF (2 ng/ml) (Lund et al, 1990; Vieira et al, 1996; Huang et al, 2004; Sigismund et al, 2008).

They are mainly browsers.

Collectors are mainly professionals.

They are mainly men.

The focus on both internalizing as well as externalizing problems reveals that there is also a significant overlap between SWB and externalizing problems, which in both males and females are mainly accounted for by genetic factors.

Cats are mainly loners.