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Detailed descriptions of each protocol are listed in Methods S1.

Primer sequences used in the RT-PCR assays are listed in Methods S2.

Primer sequences for each target gene are listed in Methods S1.

FACS antibody data, dilutions, combinations and machine specifications are listed in Methods S1.

The strains used for this work are listed in Methods S1 and Table S1.

We amplified and sequenced a broad ensemble of partially-rearranged molecules at each time interval using multiple sets of PCR primers (primer sequences are listed in Methods S1; positions are shown in Figure 3 and Figure S1).

Primers used are listed in Supplemental Methods S1.

Detailed SOPs for these protocols are listed in the Methods S1.

Antibodies used are listed in Supplementary Methods.

All sequences are listed in Supplementary Methods.

The primers used are listed in Supplementary Methods.