Sentence examples for are linked to the checkpoint from inspiring English sources

The results for our initial design for the mechanism of drug combination synergy (Figure 1e) confirmed the proposed rationale: Gemcitabine serves as a drug establishing a baseline perturbation on the inter-module network, but Bortezomib could add a more focused perturbation on key gatekeeper modules which are linked to the checkpoint perturbation established by Gemcitabine (Figure 5d).

Additionally, ies4 phosphorylation mutants are linked to the function of checkpoint regulators, such as the replication checkpoint factors Tof1 and Rad53.

The programmes are linked to the Winterthur Conservation Laboratories.

Hepatic apoptosis was, however, unchanged, and the authors suggested that downregulation of the cell cycle checkpoints may be linked to the recent finding that inhibition of checkpoint function increases stress resistance and lifespan in C. elegans (Olsen et al 2006).

Regulated by AKT and a key player in the AKT/PI3K/mTOR pathway, glycogen synthase kinase 3 beta (GSK-3), the critical checkpoint for glycogen synthesis, is linked to the circadian rhythm [ 33].

The protein product of this gene has been linked to the nuclear import of a protein important for DNA repair and checkpoint function [104], [114].

Indeed, I think that the logic behind the DNA replication checkpoint-dependent inhibition of recombinational repair is linked to the fact that the repair occurs at HR centers.

Based on its interactions, Sgol2 has been linked to cohesion protection, the spindle assembly checkpoint, and error correction pathways.

The expression of these histone genes occurs during S phase and is linked to DNA replication via S-phase checkpoints.

Other interacting proteins have previously been linked to DSB repair and/or damage-inducible checkpoints.

As activation of a meiotic checkpoint is linked to defects in eggshell patterning (Morris and Lehmann 1999), these findings suggest that oogenesis in Top2 -complementing females occurs without checkpoint activation.