Schneider JW, Aagaard K and Bloch CW (2015) What happens when national research funding is linked to differentiated publication counts?
The fact that osteoactivin is expressed in differentiated osteoblasts is consistent with human HGFIN being linked to differentiated immune cells [ 1, 6].
These developmental pathways synergize to drive EMT and invasiveness, are present in poorly differentiated lesions, and are linked to increased resistance to chemotherapeutic regimens.
Furthermore, the *6A variant might be linked to poorly differentiated breast cancer.
Morphological changes may thus be linked to expression of a differentiated phenotype for some inflammatory mediators.
The notion that MTX-induced effects upon PpIX levels in the LNCaP cells might be linked to induction of a differentiated phenotype per se remains open to conjecture.
In breast cancer, EZH2 overexpression has previously been linked to aggressive and poorly differentiated carcinomas [ 9], and downregulated DNA repair [ 10].
Several other cell cycle regulators have been linked to neuronal plasticity in fully differentiated neurons, such as the anaphase-promoting complex/cyclosome (APC/C) and its activator Cdh1, polo-like kinase 2 (Plk2), Aurora A kinase and the origin recognition complex (ORC) (reviewed in [ 29]).
Type I tumors are the most frequent subtype which have been linked to obesity, estrogen excess, and low-grade (differentiated) inflammation.
Compared to moderately and well differentiated tumors, poorly differentiated tumors (i.e. G3) were linked to a higher chance of posterior acoustic enhancement and less shadowing (31% versus 9%, p < 0.001; 25% versus 49%, p < 0.001).
Furthermore, blood group antigen genes involved in post translational protein modification and resulting in differentiated glycan fingerprints have been linked to pathogen driven selection in humans [6].
