Sentence examples for are likely to bind from inspiring English sources

Exact(49)

Most drugs and drug-like molecules are likely to bind to multiple transporters, for example; drugs are known to interact with no fewer than six targets and many proteins are known to interact with hundreds of drugs to get the biophase [ 12].

All of these compounds are likely to bind in an inter-subunit binding cavity at the top of the TMD which imposes an upper size limit upon them (Stevens et al., 2005; Nury et al., 2011).

These inhibitors do not block the N-terminal domain's ATP-binding site, and thus are likely to bind at the C-terminal domain.

Hence, these nine different descriptors are suitable for formulating a scoring function that can differentiate between small molecules that are likely to bind kinases (actives that have kinase-likeness) and those that are not.

One way to solve this question is the use of enantiomeric substances, as enantiomers have the exact same physical properties, but are likely to bind with different affinities to proteinaceous and thus chiral binding sites.

However, there are no methods available for doing this, whether with purified complexes or crude extracts, because of the complexity of the reactions: pre-splicing complexes assemble in the presence of numerous competing RNA-binding proteins, many of which have low specificity and are likely to bind dynamically and sometimes cooperatively.

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Similar(11)

The link between determining binding specificity and finding sites where the transcription factor is likely to bind is the way in which binding specificity is represented.

A binding pocket that is likely to bind a ligand will have an Sscore greater than 0.8 and a Dscore greater than 0.83 [44] 44].

CTCF is a sequence-specific Zinc-Finger DNA binding protein [28], and we thought it was likely to bind the rDNA directly.

The object was to find fragments with affinity to the ATP-binding site, which would produce a set of fragments that were likely to bind to GAK or other kinases due to the conserved nature of the ATP-binding site.

Over time, such a construct is likely to bind it more closely to advancing the good of society overall.

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