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In general, cool temperatures slow development and warm temperatures speed development, but extreme heat and cold are lethal to developing embryos.
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Interestingly, attempts to over-express IL-17 transgenically have not been successful, perhaps because of a generalized inflammation that is lethal to developing embryos [ 81].
VEGF levels are normally very tightly controlled because too little or too much VEGF can be lethal to developing embryos (Carmeliet et al. 1996; Miquerol et al. 2000).
Unrepaired DSBs are lethal to proliferating cells.
If genetic load increases because of mutations during mitotic cell divisions, very old plants should have accumulated more recessive alleles that will be lethal to young developing embryos.
In the course of developing agents of chemical warfare, some of the chemicals created in the laboratory were found to be lethal to insects.
It is lethal to witness.
This event was lethal to the crew".
Sunscreen is lethal to coral.
Its core is lethal to democracy.
These fumes can be lethal to birds.
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