Counter-intuitively, there are situations in which earlier inoculation can be less efficacious, and simultaneous inoculation with antibiotics can be detrimental.
The low doses (125 mg/kg diet) were less efficacious and did not affect tumor morphology.
A recent study showed that KBr was less efficacious and tolerable than PB as first-line drug [ 10].
Low doses of either agent were less efficacious and did not significantly increase apoptotic cells (Table 2).
Despite the greater formal education and skills of the coping interventionists and the lengthier coping treatment sessions, the Coping group nevertheless was less efficacious and less cost-effective than the Education group in effecting desirable diabetes outcomes.
Compared with CPAP, the gold standard therapy, OAs are less efficacious but are more accepted and tolerated by patients, which, in turn, may lead to a comparable level of therapeutic effectiveness.
However, these oral vaccines are less efficacious in developing countries [ 4, 5] and are associated with safety concerns such as a risk of intussusception [ 6].
Furthermore, research suggests that treatments that incorporate affect control strategies, e.g. relaxation training, distraction and benzodiazepine use, are less efficacious than exposure-based procedures over time [ 41].
Currently two RV vaccines are available and recommended for infants, but both vaccines are less efficacious in some countries in Africa and Asia.
As expected, the loss of cancer cell viability upon treatment with single-agent 0.6 μM mitoxantrone and 0.2 μM mithramycin was less than 50%, since these are less efficacious than the combination treatments.
