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The phrase "are largely validated" is correct and usable in written English.
It can be used when discussing the confirmation or support of a theory, idea, or finding by evidence or research.
Example: "The results of the study are largely validated by previous research in the field."
Alternatives: "are mostly confirmed" or "are primarily supported".
Exact(2)
This highlights a problem in basic and translational research where animal models of disease are largely validated through phenotypic similarity to human disease.
Cis-NATs derived from traditional sequencing are largely validated by other data sets, although different cis-NAT data sets have different prevalent cis-NAT topologies with respect to overlapping protein-coding genes.
Similar(58)
However, attenuation correction using CT data and bilinear conversion of HU in linear attenuation coefficients have been largely validated for PET-CT, and non-biological materials are increasingly present in scanned patients.
These claims about the typical intonation of these different types of question have been largely validated in empirical studies (Geluykens 1988; Hirschberg 2000; Hedberg and Sosa 2002; Hedberg et al. 2004).
Their early structural model of the small ribosomal subunit model was largely validated by subsequent high-resolution crystal structures [9].
To address the question of the potential differentiation-associated regulation of DNA DSBs repair activity, we took advantage of the well-established murine 3T3F442A preadipocyte cell line, which has been largely validated as a valuable model of adipogenesis [19].
This method has been largely validated and is reproducible in humans [ 40, 41].
However, it has been largely validated in Caucasians and Asians, 10, 11 but not Africans.
The three factor structure was largely validated recently in a multi-country study [ 29].
GAT was performed using a method which has been largely validated in previous studies by our group.
Current standard methods for activity calculation for both resin and glass microspheres were largely validated on empirical grounds [ 2– 8].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com