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The phrase "are largely regulated" is correct and usable in written English.
It can be used when discussing the extent to which something is controlled or governed by rules or laws.
Example: "The financial markets are largely regulated to ensure transparency and protect investors."
Alternatives: "are mainly governed" or "are primarily controlled".
Exact(37)
Nurr1 belongs to the family of steroid nuclear hormone receptors whose activities are largely regulated by co-regulators in the form of repressor (NCoR) and activator (NCoA) complexes (Xu et al, 1999).
For example, although E2F-binding elements are present in some histone gene promoters and the tumour suppressor Rb as a transcription repressor is involved in E2F-mediated transcriptional regulation, vertebrate histone genes are largely regulated by transcriptional activation rather than de-repression mechanisms (reviewed in [ 3]).
The subprime lenders are largely regulated by the states, whose laws can vary substantially.
Most of these activities are largely regulated by its molecular weight, which often triggers opposing functions.
Microbial decomposition and invertebrate comminution of a particular organic substrate are largely regulated by temperature and water availability.
Aides said they would propose new federal standards for mortgage brokers who issued many unsuitable loans and are largely regulated by state officials.
Similar(23)
Significantly up-regulated DEGs were mainly downstream targets of EGR1, JUN, MYB, RUNX1, and MYC while the significantly down-regulated DEGs were largely regulated by DDIT3, NFAT5, and SOX5 (data not shown).
Although the insurance industry is largely regulated by the states, its lobbying force in Washington is formidable.
The day-to-day management of a company is largely regulated by state law.
Theoretical prediction further suggested that the remodeling was largely regulated by the mechanical loading distribution pattern determined by implant design.
But Ms. Reno said that so far she had seen no reason to "jump in" to an issue that is largely regulated by state laws.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com