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Transgenic approaches to salt tolerance are largely achieved through the overexpression of the genes involved in Na+ exclusion from the root or leaves and Na+ compartmentalization in the vacuoles (Wang et al. 2003; Bhatnagar-Mathur et al. 2008).
However we have learned that statin's therapeutic effects are largely achieved through a remarkably wide range of actions including the ability to decrease inflammation, improve the health of arterial walls, decrease excessive clotting and stabilize atherosclerotic plaque so it doesn't flake off and cause a heart attack or stroke.
These cobenefits are largely achieved by reducing the consumption of animal products (and switching away from high-emission meats such as beef and lamb and towards lower emission meats such as pork and chicken) and savoury processed foods, while increasing consumption of cereals, fruit and vegetables.
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Gains in reducing distance traveled were largely achieved by shortening the longest commutes.
In Iraq, the aim was to defeat the insurgents, a goal that has been largely achieved.
This goal is largely achieved in the serifed, functional world of publishing.
The goal of churning out world champions was largely achieved, but at a substantial price.
And that has been largely achieved by the verbal element of his oeuvre.
Keynes's vision of everyone in the 2030s being a lot richer is largely achieved.
This turnaround has been largely achieved by British chefs trained in British colleges.
But in fact, the décor was largely achieved on a strict budget.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com