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The phrase "are known to affect" is correct and usable in written English.
It can be used when discussing the established impact or influence of something on another entity or condition.
Example: "These chemicals are known to affect the environment in various ways, leading to significant ecological changes."
Alternatives: "are recognized to influence" or "are understood to impact".
Exact(60)
In some cases these modifications are known to affect structure and are essential for function.
For example, melatonin levels are known to affect body temperature selection in reptiles.
Electric currents/voltages are known to affect bacterial cells.
Hunting and fishing are known to affect many animal populations.
Friction-induced vibrations are known to affect many engineering applications.
Anthropogenic derived stressors are known to affect seagrasses.
Cannabis and cannabinoids are known to affect female reproduction.
Organic complexing species are known to affect radionuclide mobility in the environment.
Furthermore, we have not studied wear and osteolysis, which are known to affect predominantly uncemented cups.
Epigenetic phenomena, such as DNA methylation, are known to affect transgene expression [47 49].
Those factors are known to affect proliferation, differentiation, and matrix synthesis of chondrocytes [13 16].
More suggestions(17)
are known to injure
are recognized to affect
are known to impair
are known to afflict
are known to jeopardize
are known to engage
are known to effect
are known to impact
are well known to affect
are predicted to affect
are suggested to affect
are known to fluctuate
are assumed to affect
are found to affect
are supposed to affect
are estimated to affect
are known to infect
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com