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The phrase "are irreversibly lost" is correct and usable in written English.
It can be used to describe something that cannot be recovered or restored, often in contexts related to data, memories, or opportunities.
Example: "Once the files were deleted without a backup, they are irreversibly lost."
Alternatives: "cannot be recovered" or "are permanently gone."
Exact(5)
In the absence of SP-B or SP-C, the unsaturated lipids are irreversibly lost at high surface pressures.
Interestingly, it has been suggested that hESCs progress gradually during culture from the first "naïve" state, to the second stage exhibiting XCI, then to the third state where all XCI marks are irreversibly lost [19] [19].
Hence, important environmental cues and molecular signals are irreversibly lost in ordinary neural transplantation studies.
Scientific or philosophic responses to this problem often propose a functional definition: an organism is dead when its integrative and homeostatic functions are irreversibly lost [ 32].
Advances in biotechnology have expanded the use of medical devices for permanent mechanical support of respiration and cardiac function in a process known as destination therapy when these spontaneous vital functions are irreversibly lost.
Similar(55)
Both the capacity for consciousness and the capacity to breathe will be irreversibly lost.
The Independent on Sunday, given exclusive access inside the Unesco World Heritage site, witnessed the sheer extent of the devastation and also learned of the complex and daunting task which lies ahead trying to conserve what has not been irreversibly lost.
If you change a computer or reinstall Windows your Skype history will be irreversibly lost.
In contrast oxygenated SQT were irreversibly lost in enclosure experiments which made their quantitative measurement prohibitive.
It has been found that 11.4% of accumulated energy, which equals 2160 MWh for one silo in heavy industry, is irreversibly lost.
Over extended periods (>1 week) it was possible to maintain steady-state luminescence within 5% of a pre-set value, although occasionally a non-bioluminescent "mutant" became dominant; in this case light emission was irreversibly lost.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com