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Selenium enzymes are involved in utilization of the small reducing molecules glutathione and thioredoxin.
In this category, induced genes are mostly related with glucose metabolism, while repressed genes are involved in utilization of alternative carbon sources.
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Next, they are asked if, how and why they have been involved in utilization.
Together with arabinose, also catabolism of galactose is involved in utilization of hemicellulose building blocks [ 47].
HEBP1 is induced during erythroid differentiation and the protein is likely to be involved in utilization of heme for synthesis of heme proteins [ 20].
The unique for D. phosphitoxidans Ptx-Ptd cluster is involved in inorganic phosphite oxidation and an atypical C-P lyase-coding cluster (Phn) is involved in utilization of organophosphonates.
As in C. ljungdahlii, two additional monofunctional carbon monoxide dehydrogenases (CAETHG_3005 and CAETHG_3899) are encoded in the genome of C. autoethanogenum that may also be involved in utilization of CO and CO2.
The SusR2 regulon is involved in utilization of the glucose polymer dextran, as it contains genes encoding the SusC-/SusD-like proteins, a SusE homolog, and glucan 1,3-alpha-glucosidase and dextranase (Additional file 3).
In A. nidulans, AlcA is involved in utilization of ethanol as a carbon source [ 30] and in accordance with this, the level of the AlcA protein highly increased during growth of A. fumigatus on ethanol as shown by a 2D gel electrophoresis study [ 31].
Further investigations are needed to see whether all these partially conserved loci are involved in the utilization of the same molecule.
Our comparative genomics study reveals the presence of genes that are involved in ethanolamine utilization in several Vibrio species.
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